It is regarded as the Maha Mantra – the great mantra – he has been mentioned in Kali-Santarana Upanishad.

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The Hare Krishna mantra, also referred to reverentially as the Maha Mantra ("Great Mantra"), is a 16-word Vaishnava mantra which is mentioned in the Kali-Santarana Upanishad and which from the 15th century rose to importance in the Bhakti movement following the teachings of Chaitanya Mahaprabhu.This mantra is composed of two Sanskrit names of the Supreme Being, "Krishna" and … Hare Krishna mantra – also known as the Maha mantra, or “Great" mantra – is a sacred poem recited for its ability to promote higher consciousness and God-realization.This mantra consists of the repetition of the names of three Hindu deities – Hare, Krishna and Rama. ॐ कृष्णाय नमः. The three words, namely Hara, Krishna, and Rama, are transcendental seeds of the maha-mantra, and the chanting is a spiritual call for the Lord and His internal energy Hara for giving protect the conditioned soul. RAMA RAMA, HARE HARE. HARE KRISHNA, HARE KRISHNA . The mantra is a 16-word Vaishnava mantra that goes as: Hare Krishna Hare Krishna Krishna Krishna Hare Hare Thus, the mantra is not only the supreme mantra for the modern age (the Kali-yuga mahamantra), but the supreme mantra for all ages. (Wonderful Benefits of Chanting Hare Krishna Maha Mantra) The Hare Krishna mantra, also referred to reverentially as the Maha Mantra ("Great Mantra"), is a 16-word Vaishnava mantra which is mentioned in the Kali-Santarana Upanishad and which from the 15th century rose to importance in the Bhakti movement following the teachings of Chaitanya Mahaprabhu.This mantra is composed of two Sanskrit names of the Supreme Being, "Krishna" and "Rama." Our sole objective is to assist devotees in their Krishna consciousness.However, it does require resources for us to do so. ॐ कृष्णाय नमः. HARE KRISHNA, HARE KRISHNA . The chanting is a spiritual call for the Lord and His internal energy, Hara, to give protection to the conditioned soul. This chanting of Hare Krishna, Hare Krishna, Krishna Krishna, Hare Hare, Hare Rama, Hare Rama, Rama Rama, Hare Hare is directly enacted from the spiritual platform, surpassing all lower status of consciousness, namely sensual, mental, and intellectual. Hare Krishna Maha Mantra “My dear King, although Kali-yuga is an ocean of faults, there is still one good quality about this age: Simply by chanting the Hare Kṛṣṇa mahā-mantra, one can become free from material bondage and be promoted to the transcendental kingdom.” (Srimad Bhagavatam 12.3.51)